منابع مشابه
Recent advances in the design of artificial corneas.
PURPOSE OF REVIEW Artificial corneas are being developed to meet a shortage of donor corneas and to address cases in which allografting is contraindicated. A range of artificial corneas has been developed. Here we review several newer designs and especially those inspired by naturally occurring biomaterials found with the human body and elsewhere. RECENT FINDINGS Recent trends in the developm...
متن کاملIn vivo evaluation of a novel scaffold for artificial corneas prepared by using ultrahigh hydrostatic pressure to decellularize porcine corneas
PURPOSE To evaluate the stability and biocompatibility of artificial corneal stroma that was prepared by using ultrahigh hydrostatic pressurization treatment to decellularize corneas. METHODS The porcine cornea was decellularized by two methods, a detergent method and an ultrahigh hydrostatic pressure (UHP) method. Either 1% w/v Triton X-100 or sodium dodecyl sulfate (SDS) was used for the de...
متن کاملLacerated Corneas
Methods. A radiolabeled cDNA probe of a 1(1) chain was used in slot-blot hybridization to determine the levels of a 1(1) mRNA in alkali-burned corneas. In situ hybridization was used to identify the cell types that express the a 1(1) chain. Antibodies against collagen I, a-SMA, and vimentin were used in immunohistochemical studies to determine the tissue distribution of collagen I and to identi...
متن کاملHyperthermic treatment of rabbit corneas.
Well defined heat doses (temperature X time) were applied to normal rabbit corneas in an effort to determine thermal tolerance, and to examine the effects of heat on this tissue. A purely conductive heater was chosen to minimize intraocular penetration, and avoid findings attributable to nonthermal effects of inductive sources. The etched element heater was sewn to 38 rabbit corneas. Thirty-six...
متن کاملPolymorphonuclear Invasion of Wounded Corneas
Polymorphonuclear invasion of the wounded rat cornea is quantitatively described. The inflammatory cells enter the wounded tissue during the 5th postoperative hour. They steadily increase in number until they reach a maximum between 24 and 36 hours and return to normal by about the 6th day. Six hour wounds are used to evaluate the influence of topically applied drugs on the polymorphonuclear in...
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ژورنال
عنوان ژورنال: BMJ
سال: 1999
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.318.7187.821